The Warburg Effect, widely recognized by worldwide oncology as the way that human tumors generate their sustenance, is tied into the activation of HIF1-a and vice versa.
It is somewhat of a chicken or egg question of whether anoxia forced aerobic glycolysis or whether carcinogenesis turned on aerobic/anaerobic glycolysis.
This much is true - that HIF-1a is turned on by this process, in effect making cancerous cells immune to the normal genetic programs that destroy mutated and tumorigenic cells.
Vitamin C at physiological levels in fact disables HIF-1a profoundly, thereby inhibiting carcinogenesis before the fact or after the fact.
Reduced Ascorbic Acid is the key to unlocking the nexus between Von Hippel-Lindau Factor (VHF), HIF (hypoxia induced factor), apoptosis, and the cancer disease.
Tuesday, March 24, 2009
The Warburg Effect
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