(Mark Levine's work):
PNAS 2007 paper
PNAS 2008 in vivo work
Of course, this is one of several mechanisms by which it works. So there is scientific basis and demonstration across the board from the tube to the human for the claims on high dose vitamin C.
Obviously, this doesn't end basic research or anything in the fields of immunology, devbio, and regenerative medicine that seem to be making leaps and bounds. It does go to show that there are real foundations for these claims. It is a misfortune that people use health and science as political or emotional gambits of any kind, in any kind of polemic.
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