Believe it or not, I spoke to one of the guys at Osiris at a cardiovascular medicine symposium where a large portion of the science paid attention to innate stem cells, those that originate from your own bone marrow. This is actually a failed attempt at immunizing soldiers to bacterial biowarfare agents, as MSC are largely immunosuppressive rather than antigen presenting/T-cell activating. They did find that they are immensely useful at regenerating organs to some degree or another, and preventing graft versus host disease. Maybe it was my imagination or my eyes were playing tricks on me, but I was able to induce bone marrow cells to become beating heart cells at a very, very low rate when they were co-cultured with heart muscle cells in a dish. No point in trying to be persuasive; I leave it that I performed it and saw it. Prove it or disprove it yourself. It is in theory possible to take your bone marrow white blood cells and change them into nearly any other to regenerate you with brand spanking new body parts.
Here is an engineering application of making new body parts in the case of something catastrophic happening to you that goes far beyond the capability of simple nutrition to fix. If this biotech were advanced today, no victim of catastrophe, malice, or accident would ever fret as they could literally be rebuilt with their own cells.
Growing new bones.
Columbia University's applied biology/medicine department are real pioneers - they create biology where it wasn't there before. Others look to "experts" for footing, because they themselves will not be experts. The reality is that everything is demarked and organized that wasn't demarked and organized before by very intelligent people who knew nothing about the field. They become the experts by virtue of their interest and rigor in defining something that was undefined.
Tuesday, March 30, 2010
Tuesday, March 9, 2010
Sunday, March 7, 2010
Tuesday, March 2, 2010
Gamma delta T-cells and immune enhancement
This is what not to do:Mevastatin knockdown of yd T cell and corroborates independent lab studies that show that statins are immunosuppressive so much that they are considered as anti-graft-rejection drugs in organ transplant.
Priming these cells with drugs are known to potentiate an anti-cancer effect but not without the usual culprit problems like jaw necrosis.
There are other natural and safe compounds which prime gamma delta T-cells, among which are L-theanine from regular green and black tea. The focus has been on polyphenols that have a plasma threshold much lower than their effective dose, when in fact it might be more bioavailable items in tea that are making the immune system stronger rather than a direct cytotoxic effect by molecules. This being said, these molecules with very low bioavailability may have a profound local effect that is overlooked. In the case of the gastric tract, this is not a small surface area, and it is immunologically dense. The effects of polyphenols that are not seen in plasma may actually be at work in the gut, a very large lymphoid and dendritic site in its own regard. Then there are other components like L-theanine.
By modulating these pathways without drugs, one may enhance the immune system safely and naturally against cancer.
Priming these cells with drugs are known to potentiate an anti-cancer effect but not without the usual culprit problems like jaw necrosis.
There are other natural and safe compounds which prime gamma delta T-cells, among which are L-theanine from regular green and black tea. The focus has been on polyphenols that have a plasma threshold much lower than their effective dose, when in fact it might be more bioavailable items in tea that are making the immune system stronger rather than a direct cytotoxic effect by molecules. This being said, these molecules with very low bioavailability may have a profound local effect that is overlooked. In the case of the gastric tract, this is not a small surface area, and it is immunologically dense. The effects of polyphenols that are not seen in plasma may actually be at work in the gut, a very large lymphoid and dendritic site in its own regard. Then there are other components like L-theanine.
By modulating these pathways without drugs, one may enhance the immune system safely and naturally against cancer.
Two molecular mechanisms of compensation after heart attack
If the heart survives after an ischemic heart attack, there are ways that it copes. The structural scaffold fibroblast cells remain, after the functional cells have died. These work much harder to maintain the akinetic region which is better than overt rupture, which would be lethal. The rest of the remaining heart undergoes stress and strain to maintain the difference in work, but at a cost.
Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse.
Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse.
Sunday, February 28, 2010
Money, Health, Capitalism, Socialism, Nazis, Oil, War, Evil
What does any of this have to do with each other and what is the solution?
Well, first I will tell you that anarchy and an apocalypse of the infrastructure of science is not the answer, and any intelligent person in a real position of responsibility knows that. We hope that the persons who become the self-ordained or elected figureheads of large groups of influence are not petty children in nature who hold frivolous personal feelings as guidelines to their actions in public. Unfortunately, there are many frivolous adults, some of advanced age, who accidentally usurp positions of responsibility. At the same time, we work with what we have learned to gain new knowledge which may prove old knowledge false and worthless.
Money is a construct that will always exist between groups of humanity as long as they carry individuality, and most likely they will for the duration of their existence. The problem is not one of money but one of who owes who when money is made and the interest made on loans. Rather than award people social credits, the interest loan system adds extra penalty on this to enrich those who make the loan, despite the fact that they have no more right to material ownership than the loanee except for the fact that one is informed, and the other ignorant.
In major wars, the financiers always make large profits through debts generated. So by fomenting wars, enormous debts are generated and no matter who wins, the bank gets rich at humanity's great physical, mental, and spiritual suffering. These effects are most pronounced in World War 2, and unfortunately this system is still at work today in the world. The human body and its vulnerabilities also poise a debt for each person on the planet, multiplied by every year it is alive multiplied by the arbitrary inflation of the cost of each medication. In addition, it may be a way to depopulate the planet as in the evil and publicly archived plans by certain individuals. The petrochemical industry is intimately tied to the drug industry as they are interdependent on their supply, manufacture, distribution, and financial survival. Because the petrochemical and pharmaceutical industries have carried out their activities for profit, this has spawned political lobbies.
Despite the fact that Nazi Germany and Hitler came to being through this exact same mechanism, the USA allows pharmaceutical industry lobbies to influence its most powerful leaders like wooden puppets. Certainly this is Capitalism gone too far, when it preys on its own people.
The answer is to make illegal this influence, and assure that pharmaceutical industry has stringent moral codes dedicated to human health and well being. These shouldn't be religious codes, but those based on the reality of human life and the dedication to preserving it for generations to come. It should be made clear that the pharmaceutical industry exists on the behalf of the people that outnumber it, not the other way around. Good medicine is not for saints alone, it isn't reserved for the rich, it isn't reserved for an ethnic group, it isn't reserved for a religious group. It should be available impartially and fairly to all. The physical integrity of a human being allows him or her to achieve what they may or fulfill their fate or desire in life.
This is not to say that natural health groups cannot suffer the same fate. They may become as bad, greedy, and tyrannical as a synthetic pharmaceutical corporation depending on the purity of their leaders intentions. As it is often said, few does power not ruin. So look around, do your part in human freedom,...but don't let it go to your head.
Well, first I will tell you that anarchy and an apocalypse of the infrastructure of science is not the answer, and any intelligent person in a real position of responsibility knows that. We hope that the persons who become the self-ordained or elected figureheads of large groups of influence are not petty children in nature who hold frivolous personal feelings as guidelines to their actions in public. Unfortunately, there are many frivolous adults, some of advanced age, who accidentally usurp positions of responsibility. At the same time, we work with what we have learned to gain new knowledge which may prove old knowledge false and worthless.
Money is a construct that will always exist between groups of humanity as long as they carry individuality, and most likely they will for the duration of their existence. The problem is not one of money but one of who owes who when money is made and the interest made on loans. Rather than award people social credits, the interest loan system adds extra penalty on this to enrich those who make the loan, despite the fact that they have no more right to material ownership than the loanee except for the fact that one is informed, and the other ignorant.
In major wars, the financiers always make large profits through debts generated. So by fomenting wars, enormous debts are generated and no matter who wins, the bank gets rich at humanity's great physical, mental, and spiritual suffering. These effects are most pronounced in World War 2, and unfortunately this system is still at work today in the world. The human body and its vulnerabilities also poise a debt for each person on the planet, multiplied by every year it is alive multiplied by the arbitrary inflation of the cost of each medication. In addition, it may be a way to depopulate the planet as in the evil and publicly archived plans by certain individuals. The petrochemical industry is intimately tied to the drug industry as they are interdependent on their supply, manufacture, distribution, and financial survival. Because the petrochemical and pharmaceutical industries have carried out their activities for profit, this has spawned political lobbies.
Despite the fact that Nazi Germany and Hitler came to being through this exact same mechanism, the USA allows pharmaceutical industry lobbies to influence its most powerful leaders like wooden puppets. Certainly this is Capitalism gone too far, when it preys on its own people.
The answer is to make illegal this influence, and assure that pharmaceutical industry has stringent moral codes dedicated to human health and well being. These shouldn't be religious codes, but those based on the reality of human life and the dedication to preserving it for generations to come. It should be made clear that the pharmaceutical industry exists on the behalf of the people that outnumber it, not the other way around. Good medicine is not for saints alone, it isn't reserved for the rich, it isn't reserved for an ethnic group, it isn't reserved for a religious group. It should be available impartially and fairly to all. The physical integrity of a human being allows him or her to achieve what they may or fulfill their fate or desire in life.
This is not to say that natural health groups cannot suffer the same fate. They may become as bad, greedy, and tyrannical as a synthetic pharmaceutical corporation depending on the purity of their leaders intentions. As it is often said, few does power not ruin. So look around, do your part in human freedom,...but don't let it go to your head.
Friday, February 19, 2010
What's At Stake?
If you are complacent, and uninformed, your freedom will be swept away from you in a heartbeat. Don't let these elitists insult your intelligence and use your power to vote to preserve your freedom.
The Video Document
The Video Document
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