Why would you do that???
TNF-alpha shreds your arteries and causes plaque to start forming
Chlorophyll prevents TNF-a from doing its business to you.
Therefore, green plant juice may prevent atherosclerosis.
Saturday, November 21, 2015
Sunday, November 15, 2015
Negligence. Obfuscation. Perdition. Eloquence. = NOPE
As a wise man once said, there is no long term benefit to mediocrity. If it brings you to a show, helps make money in the short term, but is totally mundane and forgettable, all that will happen is that you as a scientist will have wasted your time, maybe even your entire life into your 60's, chasing after chimeras. ghosts. illusions. nothing. By that age, it is way too late to "start fresh." At best, you will be a walking irrelevent obsolescence, rotting by the day to the grave, comfortably but kindly unknown to anybody.
What is worse is when someone intentionally ignores uncomfortable or contrary evidence. Not refutes, but ignores. Refuses to even read and acknowledge. Then obfuscation, which some quackademians are experts at, leaves a smoke screen so thick that some people give up trying to understand them, leaving them to go their merry but incorrect way. Of course, if these people are wrong, fallacious, or inaccurate, it is simply a matter of time before the world makes fools of them, flying them like a flag for others to ridicule. In this way, perdition is the fire under every good scientist's ass that should make sure they are honest. I feel the heat everyday and this does make sure that I never even entertain the thought of "fudge factor" or some white lie. Even the most eloquent liar eventually gets turned up as a ridiculous fraud which is why I would never attempt such a moronic thing. Such charlatans get written up in history to be ridiculed FOREVER.
Yet others do, for short term benefits or whatever. Not me. N.O.P.E. If someone tries to stuff words in my mouth, I will swiftly and sternly correct their dishonesty in a very public way. Have a question about my work? Ask me directly, not some crazy second-hand competitor. - John C. Cha
Don't let the clowns of NOPE tell you what I think as they do not know what I think.
What is worse is when someone intentionally ignores uncomfortable or contrary evidence. Not refutes, but ignores. Refuses to even read and acknowledge. Then obfuscation, which some quackademians are experts at, leaves a smoke screen so thick that some people give up trying to understand them, leaving them to go their merry but incorrect way. Of course, if these people are wrong, fallacious, or inaccurate, it is simply a matter of time before the world makes fools of them, flying them like a flag for others to ridicule. In this way, perdition is the fire under every good scientist's ass that should make sure they are honest. I feel the heat everyday and this does make sure that I never even entertain the thought of "fudge factor" or some white lie. Even the most eloquent liar eventually gets turned up as a ridiculous fraud which is why I would never attempt such a moronic thing. Such charlatans get written up in history to be ridiculed FOREVER.
Yet others do, for short term benefits or whatever. Not me. N.O.P.E. If someone tries to stuff words in my mouth, I will swiftly and sternly correct their dishonesty in a very public way. Have a question about my work? Ask me directly, not some crazy second-hand competitor. - John C. Cha
Don't let the clowns of NOPE tell you what I think as they do not know what I think.
Sunday, November 1, 2015
Do not take Vitamin D for flu prevention?!? A world gone mad and dishonest.
Epidemic influenza and vitamin D
With a clear link to Vitamin D deficiency and influenza having been established by the most credible doctors and scientists to have existed, we have the same message being thrown at us: Get flu shots. Just in time for "flu season" which really coincides with: temperature decrease, aridity of nasopharyngeal mucous membranes, and Vitamin D deficiency (not a weakened flu virus injection deficiency).
As in literally, weakened whole flu virus and sometimes some bonus mercury if the needles were bundled in packs rather than individually. A lot of dummies think that the flu shot is a special medicine, antibody, or nanobot going around inside you plucking off the influenza virus. The flu vaccine IS the flu virus. As these rigorous and conventionally trained doctors and scientists documented, Vitamin D deficiency caused this flu virus jab to spring into action and cause flu symptoms. The symptoms were minimal to none with lots of Vitamin D.
Yet, because Big Pharma thinks we are morons and only potential consumers, they will try to persuade us to part with our money in any way imaginable. At the top of these industries, literally the only thing that matters is money. Murder is just fine if it means preserving a financial domain. It is not a second thought. If that is okay, then the other things seem like saintly occupations by comparison. What what it be to them to lie to you about efficacy, side effects, or reason of being (money)? As all (ethical) global intelligence agencies do, they follow the money to end at the real source of crime.
With a clear link to Vitamin D deficiency and influenza having been established by the most credible doctors and scientists to have existed, we have the same message being thrown at us: Get flu shots. Just in time for "flu season" which really coincides with: temperature decrease, aridity of nasopharyngeal mucous membranes, and Vitamin D deficiency (not a weakened flu virus injection deficiency).
As in literally, weakened whole flu virus and sometimes some bonus mercury if the needles were bundled in packs rather than individually. A lot of dummies think that the flu shot is a special medicine, antibody, or nanobot going around inside you plucking off the influenza virus. The flu vaccine IS the flu virus. As these rigorous and conventionally trained doctors and scientists documented, Vitamin D deficiency caused this flu virus jab to spring into action and cause flu symptoms. The symptoms were minimal to none with lots of Vitamin D.
Yet, because Big Pharma thinks we are morons and only potential consumers, they will try to persuade us to part with our money in any way imaginable. At the top of these industries, literally the only thing that matters is money. Murder is just fine if it means preserving a financial domain. It is not a second thought. If that is okay, then the other things seem like saintly occupations by comparison. What what it be to them to lie to you about efficacy, side effects, or reason of being (money)? As all (ethical) global intelligence agencies do, they follow the money to end at the real source of crime.
Cholesterol does not cause atherosclerosis. Oxidized cholesterol byproducts do.
Here are a few things to keep in mind: 1) Cholesterol is not soluble in water or blood. A derivative of cholesterol that is soluble in blood or water is not cholesterol. 2) The only way cholesterol is moved around either in the blood or as an adduct is by the action of adding a hydrophilic protein or converting free cholesterol enzymatically to a soluble form. 3) The only way cholesterol gets to an artery wall is through a lipoprotein or the soluble form made first by a cell's action upon ingested cholesterol. 4) It has already been proven that native LDL is harmless to endothelial layers even in very high concentrations of the particle and that the oxLDL particle is the one that causes havoc to the endothelial layer.
That being said, even in the most severely diseased coronary artery disease (CAD) patient with acute coronary syndrome (ACS) presenting as angina, respiratory problems, and/or MI, the level of oxLDL is 4-5mg/dL maximally. Normally, they are half this value to none. This value of 4-5 doesn't occur until after the coronary artery disease, so how could it be that oxLDL caused the CAD? Temporally, and logically, oxLDL could not have caused CAD if it was absent beforehand.
There is no question that toxic adducts of cholesterol DO cause arteriosclerosis and the consequence is atherosclerosis. Is it an inevitable event that cholesterol becomes 25-hydroxycholesterol and cholestane-3beta, 5alpha, 6beta-triol, the culprits of endothelial aggravation? No.
It is not cholesterol, it is OXIDATION that causes these culprit oxidized cholesterol molecules to arise and cause harm. By having administered pure non-oxidized cholesterol to the artery cells with no harm, scientists made sure of the fact as early as 1976. Extending the first post, here are younger studies confirming the first.
Effect of auto-oxidation products from cholesterol on aortic smooth muscle cells: an in vitro study.
Cytotoxicity of oxidation derivatives of cholesterol on cultured aortic smooth muscle cells and their effect on cholesterol biosynthesis.
Ironically, the hydroxycholesterol and other oxygen adducts shut off cellular cholesterol synthesis, making the matter worse as your cells, especially the fastest dividing ones, make it for a mission critical reason. As the repeat, "Purified cholesterol showed no cytotoxic effect and minimal inhibition of cholesterol biosynthesis"
Inhibitory effect of cholesterol oxides on low density lipoprotein receptor gene expression.
Again, after two decades, the groups repeat that ". Pure cholesterol showed only minimal inhibition."
The question of importance is how much of the toxic oxygenated cholesterol is there in food? Who would know for something boiling around in hot oil and open air for weeks? My guess is a significant amount of cholesterol has turned to ox-cholesterol and probably stuff like that should be avoided. Minimally cooked foods, or fresh foods would have a minimum of this toxic cholesterol derivative. So indeed, the way meat is cooked may be a significant way to introduce these cholesterol-oxygen problem compounds in the blood, and these are indeed soluble.
However, like most everything, there is a reason for this artery aggravating 25-hydroxycholesterol (immune response against viruses) to exist:
Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity.
25-Hydroxycholesterols in innate and adaptive immunity.
There is an enzyme that responds to interferon by hydroxylating cholesterol. 25HC is antiviral.
Given that your blood levels of ApoB bound cholesterol are from your liver and not from a vat of oil boiling around for weeks, it would not cause any arterial injury. This is dependent on antioxidant functions preventing oxidation. These are enzymatic, such as PON and glutathione, and enteral/parenteral such as Vitamin C, E, and A.
That being said, even in the most severely diseased coronary artery disease (CAD) patient with acute coronary syndrome (ACS) presenting as angina, respiratory problems, and/or MI, the level of oxLDL is 4-5mg/dL maximally. Normally, they are half this value to none. This value of 4-5 doesn't occur until after the coronary artery disease, so how could it be that oxLDL caused the CAD? Temporally, and logically, oxLDL could not have caused CAD if it was absent beforehand.
There is no question that toxic adducts of cholesterol DO cause arteriosclerosis and the consequence is atherosclerosis. Is it an inevitable event that cholesterol becomes 25-hydroxycholesterol and cholestane-3beta, 5alpha, 6beta-triol, the culprits of endothelial aggravation? No.
It is not cholesterol, it is OXIDATION that causes these culprit oxidized cholesterol molecules to arise and cause harm. By having administered pure non-oxidized cholesterol to the artery cells with no harm, scientists made sure of the fact as early as 1976. Extending the first post, here are younger studies confirming the first.
Effect of auto-oxidation products from cholesterol on aortic smooth muscle cells: an in vitro study.
Cytotoxicity of oxidation derivatives of cholesterol on cultured aortic smooth muscle cells and their effect on cholesterol biosynthesis.
Ironically, the hydroxycholesterol and other oxygen adducts shut off cellular cholesterol synthesis, making the matter worse as your cells, especially the fastest dividing ones, make it for a mission critical reason. As the repeat, "Purified cholesterol showed no cytotoxic effect and minimal inhibition of cholesterol biosynthesis"
Inhibitory effect of cholesterol oxides on low density lipoprotein receptor gene expression.
Again, after two decades, the groups repeat that ". Pure cholesterol showed only minimal inhibition."
The question of importance is how much of the toxic oxygenated cholesterol is there in food? Who would know for something boiling around in hot oil and open air for weeks? My guess is a significant amount of cholesterol has turned to ox-cholesterol and probably stuff like that should be avoided. Minimally cooked foods, or fresh foods would have a minimum of this toxic cholesterol derivative. So indeed, the way meat is cooked may be a significant way to introduce these cholesterol-oxygen problem compounds in the blood, and these are indeed soluble.
However, like most everything, there is a reason for this artery aggravating 25-hydroxycholesterol (immune response against viruses) to exist:
Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity.
25-Hydroxycholesterols in innate and adaptive immunity.
There is an enzyme that responds to interferon by hydroxylating cholesterol. 25HC is antiviral.
Given that your blood levels of ApoB bound cholesterol are from your liver and not from a vat of oil boiling around for weeks, it would not cause any arterial injury. This is dependent on antioxidant functions preventing oxidation. These are enzymatic, such as PON and glutathione, and enteral/parenteral such as Vitamin C, E, and A.
Saturday, August 1, 2015
Pure cholesterol versus oxidized cholesterol and the role of antioxidants.
Now this is interesting. "Purified cholesterol at the same dose produced no effect." This painstaking chemistry is rare and goes to show that you can call something cholesterol, but it may not actually be cholesterol. All these oxygen adducts of cholesterol and other junk are very aggravating to the artery, causing "intimal, fibrous lesions without foam cells or hypercholesterolemia" the sort of thing you might see in advanced scorbutic lesions of the artery wall. This probably pertains to cheap Vitamin C too, which might contain some harmful junk. Pure Vitamin C of good quality, not questionable and impure, is probably as important.
Arch Pathol Lab Med. 1976 Nov;100(11):565-72. Angiotoxicity and arteriosclerosis due to contaminants of USP-grade cholesterol. Imai H, Werthessen NT, Taylor CB, Lee KT. Abstract Impurities were concentrated from several lots of cholesterol by recrystallizing cholesterol from methanol solution, retaining the mother liquor, and evaporating the residuum to dryness under vacuum. This concentrate contained the products of spontaneous oxidation of cholesterol and other contaminants from the original source. The concentrate increased the frequency of dead aortic smooth muscle cells and induced focal intimal edema in the rabbit 24 hours after gavage at 250 mg/kg. New or old cholesterol was similarly angiotoxic, the old more so than the new. Cholesterol purified via dibromination induced an increase in aggregate debris in 24 hours at 250 mg/kg but no increase in degenerated cells. The concentrate administered at a total dose of 1 gm/kg/seven weeks induced intimal, fibrous lesions without foam cells or hypercholesterolemia. Purified cholesterol at the same dose produced no effect.
The problem with food is that unless you keep it under nitrogen and don't cook any of your food, invariably there will be some oxidized cholesterol products. My arteries balk at the sight of this crud. The good news is that unlike the experimental condition above and in other experiments adding oxidized cholesterol, there isn't a whole lot of it in what you eat unless you exclusively eat low quality fast food that is fried the hell out of in oil that recirculates and boils in the air for sometimes weeks at a time, which is like an oxidation factory. Then you might worry some about oxidized cholesterol.
The good news is that there is an enzyme that can prevent LDL oxidation called paraoxonase.
Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R.
The reality is that cardiovascular disease is rampant in industrialized nations where there is plenty of fruits and vegetables available 365 days a year. If apples and oranges were the cure for heart disease, there would be no heart disease in the US. By logical deduction, it is not a lack of orange or apple, but something else.
Like a broken record, many scientists the world over have implicated that the human need for Vitamin C and other essential nutrients is much greater than what the RDA maintains, and unfortunately what food can deliver. Unless we all start eating a whole bunch of acerola cherries all the time, for example, you would need to eat 30 oranges a day or drink the equivalent of fresh squeezed juice to get a modest 2.7 grams of ascorbate. The whole point of the idea of vitamins was to cover what nutritious food, like oranges and apples could not provide, especially given that trees only fruit 3-5 months a year, leaving humans ravaged by scurvy during the non-fruiting season, therefore creating the situation "cyclical scurvy." When Vitamin C containing fruits and vegetables are available in the growing season again, the atherosclerosis accelerates during this period, not reduces, in order to build a more scurvy resistant arterial wall. You want to have a consistent optimal dose at all times.
Now that was a tangent, but not really, as serum antioxidants like Vitamin C have everything to do with preventing cholesterol oxidation and enhancing PON function. The understated and amazing observation made in 1976 is that purified cholesterol, free of oxidation products and contaminants, is harmless to the artery wall.
Arch Pathol Lab Med. 1976 Nov;100(11):565-72. Angiotoxicity and arteriosclerosis due to contaminants of USP-grade cholesterol. Imai H, Werthessen NT, Taylor CB, Lee KT. Abstract Impurities were concentrated from several lots of cholesterol by recrystallizing cholesterol from methanol solution, retaining the mother liquor, and evaporating the residuum to dryness under vacuum. This concentrate contained the products of spontaneous oxidation of cholesterol and other contaminants from the original source. The concentrate increased the frequency of dead aortic smooth muscle cells and induced focal intimal edema in the rabbit 24 hours after gavage at 250 mg/kg. New or old cholesterol was similarly angiotoxic, the old more so than the new. Cholesterol purified via dibromination induced an increase in aggregate debris in 24 hours at 250 mg/kg but no increase in degenerated cells. The concentrate administered at a total dose of 1 gm/kg/seven weeks induced intimal, fibrous lesions without foam cells or hypercholesterolemia. Purified cholesterol at the same dose produced no effect.
The problem with food is that unless you keep it under nitrogen and don't cook any of your food, invariably there will be some oxidized cholesterol products. My arteries balk at the sight of this crud. The good news is that unlike the experimental condition above and in other experiments adding oxidized cholesterol, there isn't a whole lot of it in what you eat unless you exclusively eat low quality fast food that is fried the hell out of in oil that recirculates and boils in the air for sometimes weeks at a time, which is like an oxidation factory. Then you might worry some about oxidized cholesterol.
The good news is that there is an enzyme that can prevent LDL oxidation called paraoxonase.
Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R.
The reality is that cardiovascular disease is rampant in industrialized nations where there is plenty of fruits and vegetables available 365 days a year. If apples and oranges were the cure for heart disease, there would be no heart disease in the US. By logical deduction, it is not a lack of orange or apple, but something else.
Like a broken record, many scientists the world over have implicated that the human need for Vitamin C and other essential nutrients is much greater than what the RDA maintains, and unfortunately what food can deliver. Unless we all start eating a whole bunch of acerola cherries all the time, for example, you would need to eat 30 oranges a day or drink the equivalent of fresh squeezed juice to get a modest 2.7 grams of ascorbate. The whole point of the idea of vitamins was to cover what nutritious food, like oranges and apples could not provide, especially given that trees only fruit 3-5 months a year, leaving humans ravaged by scurvy during the non-fruiting season, therefore creating the situation "cyclical scurvy." When Vitamin C containing fruits and vegetables are available in the growing season again, the atherosclerosis accelerates during this period, not reduces, in order to build a more scurvy resistant arterial wall. You want to have a consistent optimal dose at all times.
Now that was a tangent, but not really, as serum antioxidants like Vitamin C have everything to do with preventing cholesterol oxidation and enhancing PON function. The understated and amazing observation made in 1976 is that purified cholesterol, free of oxidation products and contaminants, is harmless to the artery wall.
Saturday, July 4, 2015
The Vast Need of The Human Carriage and Why Synthetic Vitamins, Especially Synthetic Vitamin C Is Necessary.
Everybody needs to run away from romantic delusions of two sorts.
One the pathetic crypto-Nazi sentiment that they or a population of humanity does not need as much Vitamin C. Given that the predicted human lifespan should easily be 150 years with vigor and youth retained at age 100, this is a laughable retrospective delusion. There is not a person on Earth who doesn't need to rescue their genetic defect in their L-Gulono-y-lactone oxidase gene. Nordic, Germanic, whatever. It doesn't include you either. You still need multi-gram quantities of ascorbate through your entire life without cessation.
The other, a naturalist idea, that we must succumb to our biological frailties because we are supposed to have them. Then there is no point to medical science and progress. It is akin to a sort of suicide, philosophical at its core, but in action a suicide. Science is intrinsically artificial and synthetic. Not everything of nature is good for humans. The loss of Vitamin C synthesis, for example, was intended to cripple humanity. Natural and Synthetic are not synonymous with "Good" and "Bad." We must wipe this illogical association from our minds. A Toshiba computer is what? Natural??
We are obliged to respect and preserve The Earth and its pristine ecologies, unpoisoned by Man, but this may also take technology to do so.
The premise is and always will be that several grams of ascorbate a day are necessary to prevent and treat human cardiovascular diseases. It is not the only element necessary. The human physiology is vastly needy with many biochemical auxotrophies crippling it, not just the Gulo gene absence. If we were replete with these substances, we would be like plants, just needing mineral water, sunshine, and carbon dioxide. We're not plants. Humans take tremendous and vast resources to support on a physiological level, but we wouldn't be the most resource intensive mammal. Certain whales take enormous food resources.
Why pretend we don't need exactly what we need? Knowing that say 4 grams of ascorbate is what all humans need minimally per day to stall or prevent heart attacks and strokes, that would mean the equivalent of Vitamin C contained in 40 oranges...a day. Is it practical to rely on orange tree or lemon tree orchards to prevent heart disease and cancer? To cut to the chase, NO. Not for us, a mammal that has been GENETICALLY HANDICAPPED. All humans possess this defect, so no proud want-to-be Nazi can gloat that they need less Vitamin C than their "lesser" peer.
Let's break it down in real-life terms and show why it is exactly about "vitamin pills." You cannot rely on vitamin pill sales and then claim that it "isn't about vitamin pills." Without the commerce element, it is ever about vitamin pills to save the human race from suffering.
Orange Orchard Logistics 101 - You need to learn this before making some stupid, embarrassing global claim about planting oranges everywhere.
In a "high density" orchard, consisting of one acre, nevermind water requirement, there are 1500 orange trees. Each will produce 300 oranges per tree at year 5, for a total of 450,000 oranges per year on one acre. Remember, this is land that is dedicated to orange and nothing and nobody else. Minus the juice, that is 45,000 grams of ascorbate per year. It seems like a great deal, but let's break it down further given real world parameters. Given ALL adults require MINIMALLY 4 grams a day, everyday for prevention of major disease, this breaks down to 45,000/4grams a day/365 days a year = Less than 31 people.
This is less than needed to keep 31 people healthy.
The population of Europe was 742,500,000 people in 2013. In order to indirectly and inefficiently make 4 grams of Vitamin C for all these individuals per year, you would need a citrus orchard of 23,951,612 acres size. This translates to 37,500 square miles of orchard or greater than the size of Wisconsin.
Given that this is feasible, and certainly there are that many orange orchards, why hasn't orange juice saved humanity from atherosclerosis?
There are about 8 oranges in a big 16 oz cup of juice, or two glasses of juice. This would be 800 mg of Vitamin C, a good beneficial dose, but hardly enough to get to the therapeutic amount of 40 oranges a day, or 5 big glasses of orange juice (plus the sugars) EVERYDAY. Not only does nobody do this, it is not tolerable. As delicious as it is, nobody can stomach such enormous quantities of orange juice. Attempting to EAT 40 oranges EVERYDAY is even worse. If you are talking apples, we're talking ten times more apples - FOUR HUNDRED APPLES A DAY = 3.4 grams Vitamin C.
Only a concentrated extract taken undiluted would be and could be effective, and this would take...SCIENCE AND TECHNOLOGY to squeeze the nutrition of 400 apples into a tolerable volume! It is deceptive and irresponsible to suggest that eating an orange or an apple a day will stave off the genetic defect all humans possess in some kind of romantic naturalism statement on behalf of somebody who does not take their vitamins, like a child who won't eat their vegetables. There is an easier solution in place, synthetic but good and pure Vitamin C, also a product of science. Naturalism, the human notion, is not always constructive or forward looking. It can plunge you backwards to square one.
One the pathetic crypto-Nazi sentiment that they or a population of humanity does not need as much Vitamin C. Given that the predicted human lifespan should easily be 150 years with vigor and youth retained at age 100, this is a laughable retrospective delusion. There is not a person on Earth who doesn't need to rescue their genetic defect in their L-Gulono-y-lactone oxidase gene. Nordic, Germanic, whatever. It doesn't include you either. You still need multi-gram quantities of ascorbate through your entire life without cessation.
The other, a naturalist idea, that we must succumb to our biological frailties because we are supposed to have them. Then there is no point to medical science and progress. It is akin to a sort of suicide, philosophical at its core, but in action a suicide. Science is intrinsically artificial and synthetic. Not everything of nature is good for humans. The loss of Vitamin C synthesis, for example, was intended to cripple humanity. Natural and Synthetic are not synonymous with "Good" and "Bad." We must wipe this illogical association from our minds. A Toshiba computer is what? Natural??
We are obliged to respect and preserve The Earth and its pristine ecologies, unpoisoned by Man, but this may also take technology to do so.
The premise is and always will be that several grams of ascorbate a day are necessary to prevent and treat human cardiovascular diseases. It is not the only element necessary. The human physiology is vastly needy with many biochemical auxotrophies crippling it, not just the Gulo gene absence. If we were replete with these substances, we would be like plants, just needing mineral water, sunshine, and carbon dioxide. We're not plants. Humans take tremendous and vast resources to support on a physiological level, but we wouldn't be the most resource intensive mammal. Certain whales take enormous food resources.
Why pretend we don't need exactly what we need? Knowing that say 4 grams of ascorbate is what all humans need minimally per day to stall or prevent heart attacks and strokes, that would mean the equivalent of Vitamin C contained in 40 oranges...a day. Is it practical to rely on orange tree or lemon tree orchards to prevent heart disease and cancer? To cut to the chase, NO. Not for us, a mammal that has been GENETICALLY HANDICAPPED. All humans possess this defect, so no proud want-to-be Nazi can gloat that they need less Vitamin C than their "lesser" peer.
Let's break it down in real-life terms and show why it is exactly about "vitamin pills." You cannot rely on vitamin pill sales and then claim that it "isn't about vitamin pills." Without the commerce element, it is ever about vitamin pills to save the human race from suffering.
Orange Orchard Logistics 101 - You need to learn this before making some stupid, embarrassing global claim about planting oranges everywhere.
This is less than needed to keep 31 people healthy.
The population of Europe was 742,500,000 people in 2013. In order to indirectly and inefficiently make 4 grams of Vitamin C for all these individuals per year, you would need a citrus orchard of 23,951,612 acres size. This translates to 37,500 square miles of orchard or greater than the size of Wisconsin.
Given that this is feasible, and certainly there are that many orange orchards, why hasn't orange juice saved humanity from atherosclerosis?
There are about 8 oranges in a big 16 oz cup of juice, or two glasses of juice. This would be 800 mg of Vitamin C, a good beneficial dose, but hardly enough to get to the therapeutic amount of 40 oranges a day, or 5 big glasses of orange juice (plus the sugars) EVERYDAY. Not only does nobody do this, it is not tolerable. As delicious as it is, nobody can stomach such enormous quantities of orange juice. Attempting to EAT 40 oranges EVERYDAY is even worse. If you are talking apples, we're talking ten times more apples - FOUR HUNDRED APPLES A DAY = 3.4 grams Vitamin C.
Only a concentrated extract taken undiluted would be and could be effective, and this would take...SCIENCE AND TECHNOLOGY to squeeze the nutrition of 400 apples into a tolerable volume! It is deceptive and irresponsible to suggest that eating an orange or an apple a day will stave off the genetic defect all humans possess in some kind of romantic naturalism statement on behalf of somebody who does not take their vitamins, like a child who won't eat their vegetables. There is an easier solution in place, synthetic but good and pure Vitamin C, also a product of science. Naturalism, the human notion, is not always constructive or forward looking. It can plunge you backwards to square one.
Atherosclerosis Is Not A Modern Disease. Lifespan Was Shorter Not Longer In Ancient Humans.
Looking at atherosclerotic plaque in people 4000 years ago.
Today we are awash with paleo diet recommendations or vegetarian/granarian/fruitarian diets, all consumed by ancient human beings. They DIDN'T live longer, they lived much shorter lives. People never reached 50 years of age, and this age was correlated with rampant atherosclerosis (plaque). They certainly had orange and apple trees back then. There is no shortage of apples in Europe, so that is clearly not the cause of atherosclerosis in Europe. It is not because of an "apple tree deficiency." Our clean eating ancestors had severe atherosclerosis before the age of 40. Why could this be? They ate plenty of apples...
The German and Norse Pagan festivals featured many many apples (to eat). "Brita as Iduna" (1901) by Carl Larsson:
We have a heritable in-born genetic defect of ascorbate synthesis that goes beyond just a sprinkle or dash. It was the great pioneers such as Pauling, Stone, Cameron, Willis, who initiated the idea of megadose ascorbate consumption (which is not mega but actually normal). The schizophrenic contradiction of wanting this threshold rescue dose of this genetic defect to be lower by the day is pure insanity. It is like saying one day humans will not need to drink several glasses of water a day to be alive. It "ain't gonna happen." The orange tree idea takes us to square one, as the therapeutic dose for atherosclerosis is minimally 4,000 mg ascorbate. That is 40 oranges, more than a tree may make all year. Until the day we as a species actually genetically engineer back a working copy (is this natural?) to replace our corrupted yet present Gulo gene, we will need to take in effective amounts of the rescue substance, ascorbate.
That is the whole idea behind science, the mastery of our biological weaknesses, and so called "vitamins." If we are naturalists to the extreme, throw away your computer, wear burlap sacks, live like a Quaker and we can forget about vitamin pills altogether, plunging ourselves all the way back to 4000 years ago where people were rife with atherosclerosis and lived to a little over 40 years of age despite "perfect" natural diets with no fried or packaged foods.
It's the missing substances, stupid.
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