Simvastatin Turns Off Phagocytosis of Bacteria Neutralized by Antibodies

The cells that gobble up bacteria that have been attacked with antibodies don't work so well after a nice good dose of LDL-lowering simvastatin.

Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus.

Collagen Tumor Capsules Break Open in Metastasis

There have been constant redefinitions of schirrhous response or the desmoplastic response in which the body encapsulates a tumor with collagen. Some would say that this was a negative prognostic, others that it was a good one. Certainly science has been confused as to the importance of "walling off" a tumor with collagen. It is not an imaginary computer graphics simulation, but a real phenomenon that is a biochemical reflex to turn an irritating mass into a benign one.

When metastasis occurs, these collagen capsules are broken open and the malignant cells spill outside, free to invade other tissues or the blood circulation. Clearly, the visual evidence suggests that the desmoplastic response is important to create a mechanical barrier, a wall, beyond which malignant tumor cells cannot pass. When these cells breach the wall, they have effectively begun to metastasize.

Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?

22 years older but still as good as new.

Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin.

Lysine Amelioration of Angina Pectoris

Photographs of Lipoprotein(a) working as a "plaster cast"

The Mighty Olive.

Olive Oil Contains Anti-Microbial Compounds

The Nasty Things That Mycoplasmas Do To Humans

Antioxidant Vitamins and Your Own Rejuvenating White Blood Cells:

There are cells that sit in your bone marrow and other places that when activated and enter your bloodstream are called "Circulating Stem Cells." All of us have a set of progenitor cells that can become various new tissue called mesenchymal stem cells, endothelial progenitor cells, and stem cells that become tissues everywhere. A general term for these stem cells inside everyone already born is "adult stem cell."

Vitamin C and E supplementation with athletic training literally gets your blood flowing, and more of your own adult stem cells enter circulation to home into injury sites and repair them.

"1. Free Radic Res. 2008 Aug;42(8):754-62.

Antioxidants increase number of progenitor endothelial cells through multiple
gene expression pathways.

Fiorito C, Rienzo M, Crimi E, Rossiello R, Balestrieri ML, Casamassimi A, Muto F,
Grimaldi V, Giovane A, Farzati B, Mancini FP, Napoli C.

Department of General Pathology, Division of Clinical Pathology,Excellence
Research Center of Cardiovascular Diseases, II University of Naples, Naples,
Italy.

To date, there is no report on the effect of antioxidants on endothelial progenitor cells (EPCs). This study shows that in vitro incubation of EPCs with vitamin C and E reverted the already well documented lowering effect of TNF-alpha on EPC number and increased p-p38 expression levels. In order to document major changes of gene expression levels and gain insight into signalling pathways, microarray analysis was performed and a significant variation of the expression of 5389 genes in EPCs following antioxidant treatment was detected. Also in vivo evidence is provided about the positive effect of antioxidant vitamins on EPCs, since vitamin C and E supplementation potentiated the physical training-induced increase of EPC number and VEGF levels. Together, these data indicate that antioxidant treatment ameliorates EPC number and causes major changes of gene expression within these cells in vitro. Furthermore, concomitant antioxidant supplementation and physical training in vivo raised the levels of circulating EPCs and serum VEGF more than physical training alone.


PMID: 18712633 [PubMed - indexed for MEDLINE]"

There are other natural ways to get your repair white blood cells into circulation from your bone marrow too. The trick is to get only as much as you need, when you need them, without collateral inflammatory damage. You need cytokines for these to exit their homes and march to their destination, but cytokines can also elicit collateral damage from an indiscriminate inflammatory response.

What you need to know about statin drugs side effects - NaturalNews.tv

What you need to know about statin drugs side effects - NaturalNews.tv

Tumor Specific Functional Protein, tNOX is selectively targeted by Vanilloid-Catechin.

There is a protein that helps tumors grow and seems to only exist upon tumor cells. EGCG, a multifunctional molecule, targets this protein, but not in the quantities that are delivered orally. Oral bioavailability of EGCG is too low on its own to attack cancer cells vigorously, but combined with vanilloids such as capsaicin may require 10-100 times less. In other words, vanilloid capsaicins and EGCG make EGCG 10 to 100 times more potent. This has been known by an independent lab since 2006.

Catechin-vanilloid synergies with potential clinical applications in cancer.

tumor NOX has drug binding site, normal NOX doesn't

What is ECTO-NOX??

Old tNOX drugs, new directions.