Sunday, February 22, 2009
Collagen Subtypes in Arterial Media Missed by Chemical Histology Stains.
The Gomori Trichrome Stain, the Pentachrome stain, and generally all other traditional chemical stains still used widely today do not stain collagen in the media. For some reason, they all stain adventitial collagen or hyper-collagenous lesions, but not the true arterial collagen.
If you perform immunohistochemistry, or better yet, electron microscopy, it is clear that an important component of the arterial media is collagen cables, subtype I and III.
This is a personal observation that applies to all of cardiovascular science, but who cares what I say. See for yourself.
The "stiff artery" due to excess collagen is a compensation for years and years of aberrant biochemical and hemodynamic situations. The alternative is "death." Stiff artery vs. death. The body's physiology chooses to trade in optimal elasticity for stiffness.
If you perform immunohistochemistry, or better yet, electron microscopy, it is clear that an important component of the arterial media is collagen cables, subtype I and III.
This is a personal observation that applies to all of cardiovascular science, but who cares what I say. See for yourself.
The "stiff artery" due to excess collagen is a compensation for years and years of aberrant biochemical and hemodynamic situations. The alternative is "death." Stiff artery vs. death. The body's physiology chooses to trade in optimal elasticity for stiffness.
Need to improve spelling and sound, but CORRECT
Coronary Artery Damage = Inflammation = Molecules to repair damage = Immune Cells to remove damaged and aberrant molecules = Plaque (which is better than thrombosis or torn artery). Repeat this over and over, and you get end-stage fatal thrombosis.
Various antioxidants are key to prevention of end-stage heart disease or preventing further damage from trans-fat diets, diabetes, etc.
His good online resource
Lipoprotein "out" is an acute phase reactant to inflammation.
Besides the liver, a relatively ignored source of plasma lipoprotein shuttle out or LDL is the colon.
Thursday, February 12, 2009
Tuesday, February 10, 2009
Yet Another Waste of Your Tax Dollars
(and mine too).
Vitamin's Don't Work (Again)
They are trying to drive home the point that you should instead get cut up, irradiated, and pilled to death at your expense and their profit.
OK now. We need well trained doctors who care. Everyone deserves to make a buck. However, fleecing sick people was never meant to be a moral or ethical business. Some of these medicines work, and others simply do not. There is a list called the WHO Essential Medicines list on which some of them work well, and others do not. This is the conventional global physician's armamentarium. Take a deep look into what they are and which ones really do something and which ones are the best we can come up with.
The fact is that the NIH libraries are chock full of studies that the media simply can't digest and share with the public regarding natural products, nutrients, and their intersection with prevention and therapy of chronic disease.
It is criminal to mislead people either way. Medicine shouldn't be a religion or a politic. I personally don't believe in championing any system in particular for its intellectual/philosophical/political aesthetic. What works well should be truthfully listed as doing such. What doesn't work should not be glossed over as a panacea just because there are millions of dollars at stake. Empirically, I have found that many natural products do work for myself and others when used properly and in the right context. Don't expect vitamin C to bring someone back from the dead, but also don't expect chemotherapy to be a wonder cure.
Vitamin's Don't Work (Again)
They are trying to drive home the point that you should instead get cut up, irradiated, and pilled to death at your expense and their profit.
OK now. We need well trained doctors who care. Everyone deserves to make a buck. However, fleecing sick people was never meant to be a moral or ethical business. Some of these medicines work, and others simply do not. There is a list called the WHO Essential Medicines list on which some of them work well, and others do not. This is the conventional global physician's armamentarium. Take a deep look into what they are and which ones really do something and which ones are the best we can come up with.
The fact is that the NIH libraries are chock full of studies that the media simply can't digest and share with the public regarding natural products, nutrients, and their intersection with prevention and therapy of chronic disease.
It is criminal to mislead people either way. Medicine shouldn't be a religion or a politic. I personally don't believe in championing any system in particular for its intellectual/philosophical/political aesthetic. What works well should be truthfully listed as doing such. What doesn't work should not be glossed over as a panacea just because there are millions of dollars at stake. Empirically, I have found that many natural products do work for myself and others when used properly and in the right context. Don't expect vitamin C to bring someone back from the dead, but also don't expect chemotherapy to be a wonder cure.
Sunday, February 8, 2009
The Importance of Mental Health
There is so much emphasis on physical health, but I think we all sometimes neglect the importance of the foundation of mental health which can help us conquer any circumstance such as physical illness.
Sometimes, the awareness and definitions of a sound and stable mind simply aren't taught to people in their youth. That is really no fault of anyone if there isn't the education there. However, if you know, it is your responsibility to take time to exercise mental health hygiene and show compassion to those who are distressed.
I got this random Google ad which I found interesting for its definition of emotional issues that sometimes plague us all in youth:
DBT Therapy
Sometimes, the awareness and definitions of a sound and stable mind simply aren't taught to people in their youth. That is really no fault of anyone if there isn't the education there. However, if you know, it is your responsibility to take time to exercise mental health hygiene and show compassion to those who are distressed.
I got this random Google ad which I found interesting for its definition of emotional issues that sometimes plague us all in youth:
DBT Therapy
While everyone was busy proving themselves on paper, Pyridoxamine has been ruled a drug!
These grandstands of petty self-absorbed adults did nothing more than divert their energies away from the real fights worth fighting. That's why the common man loathes politics sometimes. So, while they were busy stroking their insufferable egos, some groups quietly convinced the FDA to rule pyridoxamine as a drug.
Pyridoxamine, if you don't know, is one of the vitamers that make up "Vitamin B6" along with pyridoxal, and pyridoxine. All three are converted in the body to pyridoxal-5-phosphate, a naturally occurring, truly essential (as opposed to your body doesn't make it "essential") vitamin. You will die without B6.
So then, they found that it is great in diabetes and heart disease and made legal dibs on it to sell it as a drug. If it didn't work, they wouldn't have gone through the trouble. The irony of all this is that they spend the same amount of money and energy making it public that vitamins don't work while they covertly plan to sell the same.
Not to worry though. What makes pyridoxamine so special is its amine group and ability to make adducts through nucleophilic attack on carbonyls. This is not something exclusive to pyridoxamine, and you can still get this effect through several other nutrients such as L-Arginine. This is totally unpatentable and cannot be ruled a drug. If this were to happen, the USA would have officially fallen into a very dark age of legal tyranny.
Pyridoxamine, if you don't know, is one of the vitamers that make up "Vitamin B6" along with pyridoxal, and pyridoxine. All three are converted in the body to pyridoxal-5-phosphate, a naturally occurring, truly essential (as opposed to your body doesn't make it "essential") vitamin. You will die without B6.
So then, they found that it is great in diabetes and heart disease and made legal dibs on it to sell it as a drug. If it didn't work, they wouldn't have gone through the trouble. The irony of all this is that they spend the same amount of money and energy making it public that vitamins don't work while they covertly plan to sell the same.
Not to worry though. What makes pyridoxamine so special is its amine group and ability to make adducts through nucleophilic attack on carbonyls. This is not something exclusive to pyridoxamine, and you can still get this effect through several other nutrients such as L-Arginine. This is totally unpatentable and cannot be ruled a drug. If this were to happen, the USA would have officially fallen into a very dark age of legal tyranny.
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